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Histomorphometry

Histomorphometry is a fundamental technique within experimental implant research. The technique is used for estimating the quantity of e.g. bone on and around an implant. 

In order to make an histomorphometric evaluation it is necessary to make 20-30µm thin histological slices containing implant surrounded by bone. These slices need to be made according to stereological principles in order to avoid bias. The estimation of e.g. the quantity of bone on and around an impalnt is done by placing the histological slices in a microscope. A video camera on the microscope transfers a picture of the histological slice to a computer where a software programme makes it possible to estimate e.g. the quantity of bone.

Histomorphometry is a very time-consuming process. Experimental studies have shown that histomorphometry can partly be replaced by microCT scanning. However, histomorphometry is the only technique that makes it possible to discriminate between different types of bone.

 
Partner on Histomorphometry programme
Visiophram
Bøge Allé 5
2970 Hørsholm
Denmark

Phone: + 45 72402990
 
Microscope

OLYMPUS Danmark A/S
Tempovej 48-50
2750 Ballerup
Denmark

www.olympus.dk

 
Calendar

Publications
No effect of cognitive behavioral patient education for patients with pain catastrophizing before total knee arthroplasty: a randomized controlled trial.
Birch S, Stilling M, Mechlenburg I, Hansen TB.
Weight Loss Intervention Before Total Knee Replacement: A 12-Month Randomized Controlled Trial.
Liljensøe A, Laursen JO, Bliddal H, Søballe K, Mechlenburg I.
Asymmetry and pelvic movements 6 months after total hip replacement Secondary analyses from a randomized controlled trial.
Mikkelsen LR, Petersen AK, Søballe K, Mikkelsen SS, Mechlenburg I.
 Orthopaedic Research Aarhus University Hospital Palle Juul-Jensens Boulevard 99 Entrance J 8200 Aarhus N Phone: +45 7846 7471 
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