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Hard Tissue Preparation

Experimental implant research is the implantation of small implants in the bones of animals. The purpose is to examine how a given treatment effects the fixation of an implant. The fixation of an implant can, among others, be illustrated by the use of ”biomechanical push-out test” and ”histomorphometry”. In order to execute these tests, the bones containing the implants have to go through a time-consuming preparation:

The implant bone block is divided in two by means of the Exact bone saw. Half of the block is immediately frozen to -20°C and saved for later use in the "biomechanical push-out test”. The other half is dehydrated in alcohol, colored with basic fusin, and embedded in plastic (polymethylmetacrylate). When embedded, 20-30 µm thin slices are cut off the implant bone block. These slices are used for ”histomorphometric” analysis.

The preparation and cutting of bone containing implants is a technically demanding procedure performed by experienced laboratory technicians at the Orthopaedic Research Lab.

 
Band Saw

Exact Apparatebau
2000 Nordenstadt
Germany

 
Calendar

Publications
Prevalence of knee contractures is high in children with cerebral palsy in Denmark.
Klenø AN, Stisen MB, Cubel CH, Mechlenburg I, Nordbye-Nielsen K.
Total hip arthroplasty versus progressive resistance training in patients with severe hip osteoarthritis: protocol for a multicentre, parallel-group, randomised controlled superiority trial.
Frydendal T, Christensen R, Mechlenburg I, Mikkelsen LR, Overgaard S, Ingwersen KG.
Hip kinematics and kinetics in patients with femoroacetabular impingement syndrome before and 1 year after hip arthroscopic surgery. Results from the HAFAI cohort
Kierkegaard S, Mechlenburg I, Dalgas U, Lund B, Søballe K, Sørensen H.
 Orthopaedic Research Aarhus University Hospital Palle Juul-Jensens Boulevard 99 Entrance J 8200 Aarhus N Phone: +45 7846 7471 
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