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Hard Tissue Preparation

Experimental implant research is the implantation of small implants in the bones of animals. The purpose is to examine how a given treatment effects the fixation of an implant. The fixation of an implant can, among others, be illustrated by the use of ”biomechanical push-out test” and ”histomorphometry”. In order to execute these tests, the bones containing the implants have to go through a time-consuming preparation:

The implant bone block is divided in two by means of the Exact bone saw. Half of the block is immediately frozen to -20°C and saved for later use in the "biomechanical push-out test”. The other half is dehydrated in alcohol, colored with basic fusin, and embedded in plastic (polymethylmetacrylate). When embedded, 20-30 µm thin slices are cut off the implant bone block. These slices are used for ”histomorphometric” analysis.

The preparation and cutting of bone containing implants is a technically demanding procedure performed by experienced laboratory technicians at the Orthopaedic Research Lab.

 
Band Saw

Exact Apparatebau
2000 Nordenstadt
Germany

 
Calendar

Publications
Football players with hip dysplasia: The relationship between muscle strength, functional performance, self-reported sport and recreation, cartilage defects and sex. A cross-sectional study
O'Brien MJM, Kemp JL, Semciw AI, Mechlenburg I, Jacobsen JS, King MG, Scholes MJ, Lawrenson PR, Crossley K, Agricola R, Souza RB, Heerey J.
Does hip muscle strength and functional performance differ between football players with and without hip dysplasia?
O'Brien MJM, Heerey J, Semciw AI, Mechlenburg I, Jacobsen JS, King MG, Scholes MJ, Lawrenson PR, Crossley K, Agricola R, Souza RB, Kemp JL.
Pain, function and quality of life are impaired in adults undergoing periacetabular osteotomy (PAO) for hip dysplasia: a systematic review and meta-analysis.
O'Brien MJ, Semciw AI, Mechlenburg I, Tønning LC, Stewart CJ, Kemp JL.
 Orthopaedic Research Aarhus University Hospital Palle Juul-Jensens Boulevard 99 Entrance J 8200 Aarhus N Phone: +45 7846 7471 
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